Listar por autor "Leiva, José"
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The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation
Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Arrizubieta Balerdi, María Jesús ; Cucarella, Carme; Lamata, Marta; Amorena Zabalza, Beatriz ; Leiva, José; Penadés, José R.; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2001) Artículo / ArtikuluaThe enterococcal surface protein, Esp, is a high-molecular-weight surface protein of unknown function whose frequency is significantly increased among infection-derived Enterococcus faecalis isolates. In this work, a ... -
Genome expression profiling-based identification and administration efficacy of host-directed antimicrobial drugs against respiratory infection by nontypeable Haemophilus influenzae
Euba, Begoña; Moleres Apilluelo, Javier ; Segura, Víctor; Viadas Martínez, Cristina ; Morey Sancho, Pau; Moranta, David; Leiva, José; Torres, Juan de; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2015) Artículo / ArtikuluaTherapies that are safe, effective, and not vulnerable to developing resistance are highly desirable to counteract bacterial infections. Host-directed therapeutics is an antimicrobial approach alternative to conventional ... -
Inactivation of the Thymidylate synthase thyA in non-typeable Haemophilus influenzae modulates antibiotic resistance and has a strong impact on its interplay with the host airways
Rodríguez Arce, Irene ; Martí, Sara; Euba, Begoña; Fernández Calvet, Ariadna ; Moleres Apilluelo, Javier ; López López, Nahikari ; Barberán, Montserrat; Ramos Vivas, José; Tubau, Fe; Losa, Carmen; Ardanuy, Carmen; Leiva, José; Yuste, José E.; Garmendia García, Juncal (Frontiers Media, 2017) Artículo / ArtikuluaAntibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate ... -
Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection
Euba, Begoña; Moleres Apilluelo, Javier ; Viadas Martínez, Cristina ; Barberán, Montserrat; Caballero Coronado, Lucía; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Torres, Juan de; Liñares, Josefina; Leiva, José; Garmendia García, Juncal (American Society for Microbiology, 2015) Artículo / ArtikuluaNontypeable Haemophilus influenzae (NTHI) is an opportunistic pathogen that is an important cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD is an inflammatory disease of the airways, ...